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Medical Engineering Collaboration / Life Sciences

TokeOni ® : the new luciferin analogue for innovative bioluminescence imaging

Overview

Organization Name

Prof. Shojiro MAKI, The University of Electro-Communications Atsushi Miyawaki M.D., Ph.D. Laboratory for Cell Function and Dynamics, Brain Science Institute, RIKEN Satoshi Iwano, Laboratory for Cell Function and Dynamics, Brain Science Institute, RIKEN

Details

Keypoint

  • Emission at near-infrared wavelengths with high permeability to biological tissues (675 nm).
  • High water solubility in ultra-pure water.
  • High permeability of the blood brain barrier.

Benefit

  • Capable of emitting light at 675nm that enables deep measurement of 5-6 cm from the epidermis
  • Capable of analyzing areas with high blood flow, such as the brain and lungs

Market Application

  • Visualization of micro-cancer metastasis
  • Observation of infectious disease kinetics